Physiological roles of dietary glutamate signaling via gut–brain axis due to efficient digestion and absorption
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چکیده
منابع مشابه
Physiological role of dietary free glutamate in the food digestion.
Gustatory and anticipatory cephalic stimuli during a meal yield nutritional information and aid efficient food digestion. Mammals, including humans, can detect the amount of dietary protein and its quality via cephalic relay to initiate proper digestion in the upper gastrointestinal (GI) tract. In addition to gustatory stimuli, visceral sensing by the abdominal vagus conveys primary afferent nu...
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Some ingested nutrients have postingestive effects that modulate food intake and improve mood subconsciously. Here, we provide an overview of the positive postingestive effects of such nutrients, primarily L-glutamate, sugar, and lipids, with respect to behavior and brain function. We also discuss the mechanisms of brain activation resulting from signaling through the gut-brain axis. Recent stu...
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Monosodium L-glutamate (MSG) elicits a unique taste termed umami and is widely used as a flavor enhancer in various cuisines. In addition, recent studies suggest the existence of sensors for L-glutamate (Glu) and transduction molecules in the gut mucosa as well as in the oral cavity. The vagal gastric afferent responds specifically to the luminal stimulation of Glu in the stomach and regulates ...
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Although it has become clear that brush border hydrolysis and consequent utilization of the monosaccharide transport system is the predominant method of absorption of the luminal products of carbohydrate digestion in man, it now appears certain that two major mechanisms are involved in the absorption of the luminal products of protein digestion; on the one hand transport of liberated free amino...
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Prolactin-releasing peptide (PrRP) was first isolated from bovine hypothalamus, and was found to act as an endogenous ligand at the G-protein-coupled receptor 10 (GPR10 or hGR3). Although originally named as it can affect the secretion of prolactin from anterior pituitary cells, the potential functions for this peptide have been greatly expanded over the past decade. Anatomical, pharmacological...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology
سال: 2013
ISSN: 0944-1174,1435-5922
DOI: 10.1007/s00535-013-0778-1